Status:

COMPLETED

Hydroxychloroquine, Oseltamivir and Azithromycin for the Treatment of COVID-19 Infection: An RCT

Lead Sponsor:

Shehnoor Azhar

Conditions:

COVID 19

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

To evaluate the effectiveness of Hydroxychloroquine Sulfate (200 mg orally 8hr thrice a day for 5 days) vs oseltamivir (75 mg orally twice a day for 5 days) vs Azithromycin (500 mg orally daily on day...

Detailed Description

A scientific taskforce notified by the Ministry of Science and Technology of the Government of Pakistan will oversee a comprehensive cohort study. Within this cohort, a multicenter, adaptive, randomiz...

Eligibility Criteria

Inclusion

  • Confirmed SARS-CoV-2 (COVID-19) infection by a positive test result
  • Either gender
  • Symptomatic for example fever, dry Cough, difficulty to breathe

Exclusion

  • Confirmed absence of SARS-CoV-2 (COVID-19) infection by a negative test result
  • Have chronic conditions such as heart disease, liver and kidney failure
  • Pregnant or currently lactating
  • Immunocompromise and/or systemic disease(s)
  • On other antiviral drugs
  • History of allergy to any of the drugs to be administered in this study

Key Trial Info

Start Date :

April 22 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 22 2020

Estimated Enrollment :

550 Patients enrolled

Trial Details

Trial ID

NCT04338698

Start Date

April 22 2020

End Date

November 22 2020

Last Update

February 10 2022

Active Locations (11)

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Page 1 of 3 (11 locations)

1

Gujranwala Medical College

Chak Two Hundred Fourteen, Pakistan

2

Nawaz Sharif Medical College

Dhok Gujra, Pakistan

3

Faislabad Medical University

Faisalābad, Pakistan

4

Szabmu-Pims

Islamabad, Pakistan