Status:

UNKNOWN

Registry to Investigate the Efficacy and Safety of VenaBlock VeIn SEaling System for VaRicose Veins in SingApore

Lead Sponsor:

Singapore General Hospital

Conditions:

Varicose Veins

Venous Reflux

Eligibility:

All Genders

21-90 years

Brief Summary

To assess the efficacy of the Venablock©Vein Sealing System (VBVS) for the treatment of lower extremity superficial truncal veins in a real-world clinical setting in a multi-racial Asian population in...

Detailed Description

The purpose of the Registry to Investigate the Efficacy and Safety of Venablock©Vein Sealing System for Varicose Veins in Singapore (RIVERIA), is to investigate the performance of cyanoacrylate glue c...

Eligibility Criteria

Inclusion

  • Age \> 21 years old and ability to understand the requirements of the study and to provide informed consent
  • C2-C6 varicose veins/CVI (CEAP Class 1 patients will be excluded)
  • Symptomatic primary GSV,SSV or AASV incompetence, with reflux \> 0.5 seconds on colour Duplex, including one or more of the following symptoms: aching, throbbing, heaviness, fatigue, pruritus, night cramps, restlessness, generalized pain or discomfort, swelling
  • Patients who had GSV, SSV or AASV diameters of 3mm to 12mm in the standing position

Exclusion

  • Current DVT or history of DVT
  • Pregnant patients
  • Arterial disease (ABPI\<0.8)
  • Sepsis
  • Patient who are unwilling to participate
  • Inability or unwillingness to complete the time-point questionnaires
  • Adverse reaction to sclerosant or cyanoacrylate previously
  • Multiple drug allergies
  • Previous intervention with the VenaSeal cyanoacrylate glue closure system
  • Severely tortuous GSV, SSV or AASV
  • Life expectancy \< 1 year
  • Active treatment for malignancy other than non-melanoma skin cancer
  • Current, regular use of systemic anticoagulation (e.g., warfarin, heparin)
  • Daily use of narcotic analgesia or NSAIDS to control pain associated with venous disease

Key Trial Info

Start Date :

October 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 1 2021

Estimated Enrollment :

30 Patients enrolled

Trial Details

Trial ID

NCT04339075

Start Date

October 1 2019

End Date

October 1 2021

Last Update

November 2 2020

Active Locations (1)

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1

Singapre General Hospital

Singapore, Singapore, 169608