Status:
COMPLETED
Electrophysiological Evaluation of Motor Dysfunction in Liver Cirrhotic Patients
Lead Sponsor:
Kasr El Aini Hospital
Conditions:
Liver Cirrhoses
Peripheral Neuropathy
Eligibility:
All Genders
18-60 years
Brief Summary
cross sectional observational study, aimed to assess the electrophysiological function of the motor units in liver cirrhotic patients.
Detailed Description
Liver cirrhosis is a global health problem which could be associated with several neurological manifestations. The associated peripheral neuropathy could be assessed by conventional nerve conduction s...
Eligibility Criteria
Inclusion
- Both genders.
- Age interval range between 18 and 60 years (To avoid maturational changes and aging process on motor unit number).
- Liver cirrhotic patients( including compensated and decompensated patients);
- Presenting hematemesis/melena and/or ascites.
- Diagnosis of liver cirrhosis is confirmed by abdominal ultrasound
Exclusion
- Patients with identifiable cause of peripheral neuropathy (e.g. diabetic patients) .
- Patients who developed hepatocellular carcinoma (to avoid para-neoplastic syndrome e.g. peripheral neuropathy)
- Patients with other non-hepatic chronic illness such as: patients with renal disease (to avoid other causes of metabolic neuropathies).
Key Trial Info
Start Date :
August 1 2018
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 5 2020
Estimated Enrollment :
56 Patients enrolled
Trial Details
Trial ID
NCT04340999
Start Date
August 1 2018
End Date
March 5 2020
Last Update
April 10 2020
Active Locations (1)
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1
Kasr Alainy Teaching Hospital-Clinical Neurophysiology Unit
Giza, Egypt