Status:

UNKNOWN

Perioperative Evaluation of Glucose Profile Using Continuous Glucose Monitoring System in Glucose Intolerant Patients

Lead Sponsor:

University Hospital, Lille

Conditions:

Hyperglycaemia (Diabetic)

Bariatric Surgery Candidate

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The recent use of a pre-operative carbohydrate loading compared to fasting has been shown to improve the early recovery after surgical procedures by reducing the profound stress response following sur...

Detailed Description

Bariatric surgery allows weight loss and obesity related comorbidities remission. In patients with type 2 diabetes (T2D), glucose intolerance (GI) and metabolic syndrome (MS), weight loss surgery impr...

Eligibility Criteria

Inclusion

  • Bariatric surgery planned (RYGB or SG)
  • BMI at least 35 kg/m2 with comorbidity that can be improved after surgery(including cardiovascular disease including high blood pressure, obstructive sleep apnea syndrome and other severe respiratory disorders, severe metabolic disorders, particularly type 2 diabetes, disabling osteoarticular disease, steatohepatitis non-alcoholic)
  • Glucose Intolerance as defined by the American Diabetes Association (ADA Diabetes Care 2017)
  • Negative pregnancy test
  • Informed consent
  • Patient with social insurance

Exclusion

  • Patients receiving insulin therapy
  • Previous bariatric surgery
  • Definite symptoms of gastroparesis assessed by Gastroparesis Cardinal Symptoms Index (GCSI)\*. Values of score ≥ 1.90 will be chosen as definite symptoms of gastroparesis.
  • Pregnant or breastfeeding woman, persons deprived of their liberty, persons under guardianship or trusteeship

Key Trial Info

Start Date :

September 1 2022

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2024

Estimated Enrollment :

76 Patients enrolled

Trial Details

Trial ID

NCT04343040

Start Date

September 1 2022

End Date

December 1 2024

Last Update

March 15 2022

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