Status:

RECRUITING

Generating Novel Therapeutic Strategies Based on Evolutionary Tumor Board

Lead Sponsor:

H. Lee Moffitt Cancer Center and Research Institute

Conditions:

Incurable Disease

Eligibility:

All Genders

Brief Summary

This study will evaluate the ability of a multidisciplinary group, the Evolutionary Tumor Board (ETB), to develop therapeutic strategies in patients without curative options.

Eligibility Criteria

Inclusion

  • Participant must be considered likely incurable given a standard of care. This is inclusive of participants in remission but at high risk of recurrence, with suboptimal responses to previous therapy, or with many potentially beneficial, but not curative options for care.
  • Participant must have a life expectancy greater than 3 months
  • Participant must have an ECOG performance status 0-2
  • Participant and primary Oncologist are willing to consider the therapeutic strategies recommended by the ETB
  • Willingness to be followed over time and allowing collection of clinical data including scans and serial blood sampling.

Exclusion

  • None

Key Trial Info

Start Date :

May 5 2020

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

March 1 2028

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT04343365

Start Date

May 5 2020

End Date

March 1 2028

Last Update

January 8 2026

Active Locations (1)

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1

Moffitt Cancer Center

Tampa, Florida, United States, 33613