Status:
UNKNOWN
A Study to Assess the Virus RNA, and miRNA Levels Related to Viral Infection, and Inflammatory Response in Tears of Patients Affected by COVID-19 Disease
Lead Sponsor:
G. d'Annunzio University
Conditions:
COVID
Conjunctivitis
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this study is to assess the virus RNA, and miRNA levels related to viral infection, and inflammatory response in tears of hospitalized patients with a diagnosis of COVID-19 with and without...
Detailed Description
The SARS-CoV-2 is a virus highly infectious whose main target of infection is the respiratory tract. Virus has been reported to target other mucus tissues, such as the conjunctiva of the eye and cause...
Eligibility Criteria
Inclusion
- Inclusion Criteria (Group 1):
- A confirmed diagnosis of COVID-19 disease
- Age ≥ of 18 years.
- absence of conjuntivitis detected by portable slit lamp
- Inclusion Criteria (Group 2):
- A confirmed diagnosis of COVID-19 disease
- Age ≥ of 18 years.
- Presence of bilateral conjunctivitis defined as red eyes (macroscopic signs of conjunctival congestion)
- Exclusion Criteria (both groups):
- Pregnant women
- Any form Ocular surface diseases preceding Covid-19 diagnosis, Glaucoma, history of anterior segment inflammation, previous penetrating ocular trauma
- Ocular surgeries within previous 6 months
- Topical therapies
- History of ocular allergy
Exclusion
Key Trial Info
Start Date :
April 14 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
April 30 2020
Estimated Enrollment :
25 Patients enrolled
Trial Details
Trial ID
NCT04346160
Start Date
April 14 2020
End Date
April 30 2020
Last Update
April 20 2020
Active Locations (1)
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1
Ophtalmology Clinic, G.d'Annunzio University
Chieti, Italy, 66013