Status:
WITHDRAWN
Acupuncture Treatment on Cerebral Blood Flow
Lead Sponsor:
University of Oklahoma
Conditions:
High Blood Pressure
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
Cerebrovascular diseases (CVD) and neurodegenerative diseases (NDD) are both leading causes of death in the United States. Epidemiological data have shown that increased prevalence of hypertension is ...
Detailed Description
After IRB approval, experiments will take place in the Human Circulation Research Laboratory in the Department of Health and Exercise on the OU Norman campus. All subjects will complete a total of 3 v...
Eligibility Criteria
Inclusion
- Subjects will include healthy controls (CON) and Hypertension (HTN) patients between 18-65 years of age. Female participants if premenopausal will be studied in the early follicular phase of their cycle to minimize vascular effects of circulating hormones.
- HTN:
- 1\) Stage 1 hypertensive, Systolic BP (SBP) ≥ 130 mmHg and/or Diastolic BP (DBP) \> 80 mmHg, and/or diagnosis of HTN, with BMI and physical activity levels ≈ CON
- If they are on anti-hypertensive medication, the dose, type, and frequency of use will be recorded.
- HTN with an SBP \> 139 mmHg must have a medical doctor's permission to participate
- CON: will be age, BMI, menstrual status for females, and physical activity matched to HTN. They must be:
- Normotensive
- Free of cardiovascular comorbidities.
Exclusion
- Diabetes
- Coronary artery disease
- Stroke
- Heart attack
- Sleep apnea
- Tobacco use
- Asthma
- Pregnancy
- Currently receiving antihypertensive acupuncture treatment
- conditions where acupuncture might not be safe, such as metal allergy or needle-phobia. If a subject experiences severe acupuncture-associated response, it will be subject to early termination of the study.
Key Trial Info
Start Date :
May 9 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 5 2022
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04346511
Start Date
May 9 2020
End Date
December 5 2022
Last Update
November 30 2023
Active Locations (1)
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1
Department of Health and Exercise Science
Norman, Oklahoma, United States, 73019