Status:
TERMINATED
Post-Exposure Prophylaxis for Asymptomatic SARS-CoV-2 COVID-19 Patients With choloroquinE Compounds
Lead Sponsor:
Government of Punjab, Specialized Healthcare and Medical Education Department
Collaborating Sponsors:
Mayo Hospital Lahore
Services Institute of Medical Sciences, Pakistan
Conditions:
SARS-CoV-2
Coronavirus Infection
Eligibility:
All Genders
20-50 years
Phase:
PHASE4
Brief Summary
To create a protocol for treatment of Pakistani patients with SARS-CoV-2 infection with an intent to reduce burden on institutional healthcare services by determining efficacy of different quinone dru...
Eligibility Criteria
Inclusion
- Nasopharyngeal RT-PCR positive SARS-CoV-2 patient
- Age 20-50 years
- BMI 18-28 kg/m2
- Informed consent
Exclusion
- Symptoms: Cough, fever, shortness of breath
- O2 saturation by pulse-oximeter below 94%
- Co-morbidities: any pre-existing cardiac disease, pulmonary disease, diabetes
- Arrhythmias and/or history of arrythmia
- Psoriasis and/or history of psoriasis
- Neuropathy or myopathy and/or history of these
- Hypoglycemia and/or history of hypoglycemia
- Pre-existing hepatic disease
- Pre-existing renal disease
- Use of antacids within 1 week
- Use of antibiotics within 1 week
- Pregnancy
- RT-PCR performed \>3 days prior to enrollment
Key Trial Info
Start Date :
April 14 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 30 2020
Estimated Enrollment :
125 Patients enrolled
Trial Details
Trial ID
NCT04346667
Start Date
April 14 2020
End Date
August 30 2020
Last Update
March 10 2021
Active Locations (3)
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1
Expo Covid Center
Lahore, Punjab Province, Pakistan
2
Mayo Hospital
Lahore, Punjab Province, Pakistan
3
Pakistan Kidney and Liver Institute
Lahore, Punjab Province, Pakistan