Status:
COMPLETED
Transmissibility and Viral Load of SARS-CoV-2 in Oral Secretions
Lead Sponsor:
National Institute of Dental and Craniofacial Research (NIDCR)
Conditions:
COVID-19
Eligibility:
All Genders
18+ years
Brief Summary
Background: COVID-19 is a worldwide pandemic and currently there is no effective therapy or vaccine. SARS-CoV-2, the virus that causes the COVID-19 respiratory infection, appears to be very contagiou...
Detailed Description
COVID-19 is a worldwide pandemic without an effective therapy. A series of reports have implicated that asymptomatic transmission occurs in at least 25% SARS-CoV-2 cases. We hypothesize that droplet e...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- In order to be eligible to participate in this study, an individual must meet all the following criteria:
- Willing and able to sign and date the informed consent form
- Willing to comply with all study procedures and available for study visits and calls
- Male or female, aged \>= 18 years of age
- Persons who test COVID-19 positive in past 48 hours (verbal confirmation followed by documented test results, sent electronically) and are asymptomatic or have mild symptoms (e.g., fever, mild malaise, sore throat or sneezing) individuals who have re-tested and are negative may be enrolled to understand progression and resolution of disease; persons hospitalized at the NIH Clinical Center meeting Inclusion Criteria 1-3 may be enrolled on this study
- Persons considered high risk for COVID-19 due to personal contact within the past 7 days with a COVID-19 positive individual (e.g., co-habitating family member of COVID-19 positive) and has no symptoms or mild symptoms of COVID-19 - verbal confirmation followed by documented test results of positive individual, sent electronically
- EXCLUSION CRITERION:
- An individual who meets any of the following criteria will be excluded from participation in this study:
- 1\. COVID-19 positive subjects with active moderate or severe symptoms of cough or shortness of breath (upper and lower respiratory symptoms) or currently requiring hospitalization at a hospital other than NIH Clinical Center (recovering COVID-19 positive patients can be enrolled).
Exclusion
Key Trial Info
Start Date :
April 16 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 27 2022
Estimated Enrollment :
55 Patients enrolled
Trial Details
Trial ID
NCT04348240
Start Date
April 16 2020
End Date
January 27 2022
Last Update
April 22 2025
Active Locations (1)
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1
National Institutes of Health Clinical Center
Bethesda, Maryland, United States, 20892