Status:

TERMINATED

Onabotulinum Dose Comparison in Chronic Migraine Superior to 100 Units?

Lead Sponsor:

United States Naval Medical Center, San Diego

Conditions:

Chronic Migraine, Headache

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The study will enroll patients through the Neurology Department at Naval Medical Center San Diego (NMCSD). Eligible participants will meet criteria for chronic migraine, but will not be excluded based...

Eligibility Criteria

Inclusion

  • Chronic migraine headache - Diagnostic criteria:
  • A. Headache (tension-type-like and/or migraine-like) on 15 days per month for \>3 months2 and fulfilling criteria B and C B. Occurring in a patient who has had at least five attacks fulfilling criteria B-D for 1.1 Migraine without aura and/or criteria B and C for 1.2 Migraine with aura
  • C. On 8 days per month for \>3 months, fulfilling any of the following 3 :
  • criteria C and D for 1.1 Migraine without aura
  • criteria B and C for 1.2 Migraine with aura
  • believed by the patient to be migraine at onset and relieved by a triptan or ergot derivative D. Not better accounted for by another ICHD-3 diagnosis. -

Exclusion

  • Previous exposure at any time to any botulinum toxin serotype Pregnancy, breastfeeding or plans to become pregnant within 6 months Age \<18 years Failure to complete at least 20 days of headache diary in the 28 day baseline period

Key Trial Info

Start Date :

May 12 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2022

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT04349176

Start Date

May 12 2017

End Date

December 31 2022

Last Update

February 5 2024

Active Locations (1)

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Naval Medical Center San Diego

San Diego, California, United States, 92134