Status:
COMPLETED
Efficacy of Diacerein on Ocular Surface Disease in Degenerative Arthritis Patients
Lead Sponsor:
Chulalongkorn University
Conditions:
Ocular Surface Disease
Osteoarthritis
Eligibility:
All Genders
18+ years
Brief Summary
Dry eyes is multi-factorial disease which inflammation play etiological role. Diacerein is drug which has anti-inflammatory effect by antagonist Interleukin-1, decrease Interleukin-1 receptor, increas...
Eligibility Criteria
Inclusion
- Osteoarthritis with
- Ocular surface index score ≥ 13 with
- Corneal staining score ≥ 3
Exclusion
- Allergic to diacerein
- Use Cyclosporin within 30 days
- Eyelid problem
- Change artificial tear while in the study
- Pregnancy or breast feeding
Key Trial Info
Start Date :
October 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
July 31 2020
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT04351100
Start Date
October 1 2019
End Date
July 31 2020
Last Update
August 10 2021
Active Locations (1)
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1
Faculty of medicine, Chulalongkorn university
Bangkok, Thailand, 10330