Status:

COMPLETED

Intestinal Permeability, Nutritional Status and Quality of Life in Celiac Disease

Lead Sponsor:

Marmara University

Conditions:

Celiac Disease

Nutritional Deficiency

Eligibility:

All Genders

18-64 years

Brief Summary

Celiac disease is defined as an autoimmune enteropathy with malabsorption of gluten protein. In recent studies, it has been stated that in individuals diagnosed with celiac disease, intestinal epithel...

Detailed Description

Celiac disease is defined as an autoimmune enteropathy that progresses with malabsorption of gluten protein found in wheat, barley, rye and small intestinal mucosal inflammation in individuals with ge...

Eligibility Criteria

Inclusion

  • To be between the ages of 18-64,
  • To be literate,
  • To have positive serological anti tissue transglutaminase immunoglobulin A antibodies value,
  • To have a small intestinal biopsy proven celiac disease diagnosis at the time of gastrointestinal endoscopy
  • To be volunteer by signing the informed consent form.

Exclusion

  • To have another autoimmune disease such as type 1 diabetes, psoriasis, hashimoto's thyroiditis, rheumatoid arthritis, systemic lupus erythematosus,
  • To be in pregnancy or lactation period,
  • Taking probiotic/ prebiotics supplements in the last 2 months,
  • Taking antibiotics or non-steroidal antiinflammatory drugs in the last 1 week.

Key Trial Info

Start Date :

November 5 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

April 19 2019

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT04351828

Start Date

November 5 2018

End Date

April 19 2019

Last Update

April 21 2020

Active Locations (1)

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Marmara University Institute of Health Sciences

Istanbul, Maltepe, Turkey (Türkiye), 34