Status:
COMPLETED
Cardiovascular and Renal Biomarkers to Predict Acute Heart or Kidney Injury in Severe Covid-19 Infection
Lead Sponsor:
Central Hospital, Nancy, France
Conditions:
COVID 19
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The Nancy Cov-H-AKI: study is a prospective, non-randomized, monocenter study performed in patients hospitalised for either the severe or the critical form of Covid-19. The main objective of the Nanc...
Detailed Description
Secondary objectives Evaluate the association of the concentrations at inclusion AND of the variations (between inclusion and 72H post-inclusion) of blood and urine cardiovascular-renal biomarkers of...
Eligibility Criteria
Inclusion
- Patients over the age of 18,
- Admission for less than 3 days in the medical service (or in intensive care) for proven serious form of Covid 19 infection (respiratory rate \>30 / min, or desaturation in air ≤ 93%, or PaO2 / FiO2 ≤ 300mmHg)
- OR Admission for less than 2 days in intensive care (or resuscitation intensive care) for critical form of Covid 19 (shock or respiratory failure).
- GFR greater than 30 ml / min / 1.73m2.
- Troponin \<99th percentile.
- Patient affiliated to a social security scheme or beneficiary of such a scheme
- The patient or their representative received complete information on the study and signed and dated the emergency situation informed consent/inclusion form in accordance with article L1122-1-3 of the French Public Health Code (Code de la Santé Publique).
Exclusion
- Exclusion criterion for patients taking part in clinical research.
- AKI KDIGO grade 1 on the day of visit 1
- Pregnant women, parturient, or nursing mothers
- A person of full age subject to a legal protection measure (guardianship, curatorship, safeguard of justice)
- Person deprived of their liberty by a judicial or administrative decision,
- Person undergoing psychiatric treatment under articles L. 3212-1 and L. 3213-1 of the Public Health Code.
Key Trial Info
Start Date :
April 27 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 26 2021
Estimated Enrollment :
73 Patients enrolled
Trial Details
Trial ID
NCT04354610
Start Date
April 27 2020
End Date
March 26 2021
Last Update
October 1 2021
Active Locations (2)
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1
CHRU de Nancy
Nancy, France, 54000
2
CHRU de Nancy
Vandœuvre-lès-Nancy, France, 54500