Status:
COMPLETED
Study of Immune Response During SARS-CoV-2 Infection - (COVID-19)
Lead Sponsor:
Centre Hospitalier Universitaire de Nice
Conditions:
New Coronavirus Disease (COVID-19), Infection With SARS-CoV-2
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Study of the cellular immune response during the SARS-CoV-2 infection and identify cytokinic profiles in caregivers exposed to the virus with asymptomatic forms of COVID19, patients with an asymptomat...
Detailed Description
Since March 2020, Europe has been facing the spread of Coronavirus disease 2019 (COVID-19), an emerging infectious disease of viral zoonosis type, caused by the coronavirus SARS-CoV-21. This virus is ...
Eligibility Criteria
Inclusion
- 1/ Medical personnel exposed to SARS-CoV-2 infection
- Inclusion criteria:
- Every willing member of medical personnel who is in charge of care, treatment or transfer of patients with COVID-19, in the hospitals of Nice, Cannes and Antibes
- The absence of infection with SARS-CoV-2 at enrolment
- Age \> 18 years
- Having signed an informed consent
- Valid health insurance
- Non-inclusion criteria:
- Age \< 18 years
- Under custody, in prison or diagnosed with a mental illness
- Refusal to give informed consent or its withdrawal
- Pregnant or breastfeeding
- Known immunodeficiency
- Previous immunosuppressive therapy
- 2\) Subjects hospitalized for a SARS-CoV-2 infection
- Inclusion criteria:
- All adult patients hospitalized in the intensive care or in infectious diseases units, or receiving follow-up at the dermatology unit, in Nice University Hospital, diagnosed with COVID-19 (as defined by the positivity to SARS-CoV-2 by two PCR multiplex)
- Age \> 18 years
- Having signed an informed consent
- Non-inclusion criteria:
- Age \< 18 years
- Under custody, in prison or diagnosed with a mental illness
- Refusal to give informed consent or its withdrawal
- Pregnant or breastfeeding
- Known immunodeficiency
- Previous immunosuppressive therapy
Exclusion
Key Trial Info
Start Date :
May 5 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 22 2022
Estimated Enrollment :
303 Patients enrolled
Trial Details
Trial ID
NCT04355351
Start Date
May 5 2020
End Date
June 22 2022
Last Update
May 17 2024
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Antibes Hospital
Antibes, France
2
Cannes Hospital
Cannes, France
3
Nice Hospital
Nice, France, 06000