Status:

UNKNOWN

Long-term Use of Drugs That Could Prevent the Risk of Serious COVID-19 Infections or Make it Worse

Lead Sponsor:

Assistance Publique - Hôpitaux de Paris

Collaborating Sponsors:

GIS EPI-PHARE

Conditions:

AMD, ACEi's/ARB Prevent/Worsen Risk of COVID-19 Infection

Eligibility:

All Genders

18+ years

Brief Summary

The COVID-19 emerging disease due to a novel coronavirus (SARS-CoV-2), started in Wuhan, China, last December, 2019. In the past three months, the virus has spread rapidly worldwide to reach the pande...

Detailed Description

Details for "Study design" section Time perspective : Retrospective and prospective cohort study using French National Health Database Data source Enrollment: * 70,000 patients treated by synthetic...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • All adults (18 years of age and older) registered in the French national health insurance database (SNDS) receiving between January 1, 2020, and May 31, 2020:
  • Synthetic anti-malarial drugs (AMD): Participants will be identified by the prescription of at least one synthetic AMD (chloroquine and hydroxychloroquine, ATC P01D1 and M01C respectively)
  • Anti-hypertensive drugs: Participants will be identified by the prescription of at least one Angiotensin receptor-blocking or Angiotensin converting- enzyme inhibitors, ATC C09A-D
  • No Exclusion Criteria

Exclusion

    Key Trial Info

    Start Date :

    April 1 2020

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    June 1 2020

    Estimated Enrollment :

    6000000 Patients enrolled

    Trial Details

    Trial ID

    NCT04356417

    Start Date

    April 1 2020

    End Date

    June 1 2020

    Last Update

    April 22 2020

    Active Locations (1)

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    Assistance Publique Hôpitaux de Paris - CHU Henri Mondor

    Créteil, France, 94000