Status:
COMPLETED
Analysis of the Coagulopathy Developed by COVID-19 Infected Patients
Lead Sponsor:
Centre Hospitalier Universitaire de Nīmes
Conditions:
Sepsis
Blood Coagulation Disorders
Eligibility:
All Genders
18+ years
Brief Summary
Increased D-dimers at admission of COVID-19 infected patients entering hospital due to a severe disease is a risk factor for death. Understanding this acquired coagulopathy is a prerequisite before sp...
Detailed Description
Accumulating data describe, in COVID-19 severely infected patients necessitating hospitalized medical support, the development of an acquired coagulopathy, from a sepsis-induced coagulopathy to an ove...
Eligibility Criteria
Inclusion
- Patient with SARS-CoV-2 infection entering hospitalization with or without resuscitation
- The patient (or their carer) must have given their free and informed consent and signed the consent form
- The patient must be a member or beneficiary of a health insurance plan
Exclusion
- Pregnant or breastfeeding patient
- It is impossible to give the subject informed information
- The patient is under safeguard of justice or state guardianship
- Thrombotic events during treatment: flare-up of venous thromboembolism, flare-up of atherothrombosis.
- Long-term anticoagulant treatment (anti-vitamin K, direct oral anticoagulant).
- Chronic anti-aggregation treatment.
- Pre-existing constitutive or acquired known coagulation pathology: hemorrhagic diseases (thrombocytopenia, thrombocytopathy, hemophilia, von Willebrand's disease, hemorrhagiparous factor deficiency), and for thrombophilia (deficits in antithrombin, protein C or S , Factor V Leiden or Prothrombin 20201A mutation).
Key Trial Info
Start Date :
April 28 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 14 2022
Estimated Enrollment :
175 Patients enrolled
Trial Details
Trial ID
NCT04356950
Start Date
April 28 2020
End Date
February 14 2022
Last Update
December 4 2025
Active Locations (4)
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1
CHU de Bordeaux
Bordeaux, France
2
CHU de Limoges
Limoges, France
3
CHU de Montpellier
Montpellier, France
4
CHU de Nimes
Nîmes, France