Status:

COMPLETED

Influence of Opioids on Circulating Tumor Cells in Radical Cystectomy

Lead Sponsor:

RenJi Hospital

Conditions:

Bladder Cancer

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Multiple lines of evidence have shown that perioperative opioids requirement was associated with poor outcomes in cancer patients, including increased cancer progression and metastases and reduced sur...

Eligibility Criteria

Inclusion

  • Age \>=18
  • ASA I-II
  • Patients with primary bladder cancer of Stage T2a or higher, who are scheduled for robot-assisted laparoscopic radical cystectomy
  • Written informed consent

Exclusion

  • Emergency surgery
  • Palliative surgery
  • Contraindications for epidural anesthesia
  • Metastatic bladder cancer
  • Patients with a history of any other malignancy
  • Chronic opioids medication
  • severe systemic disease (heart, lung, kidney, or immune system)
  • Known hypersensitivity or suspected allergy to intervention drugs
  • Intellectual Disability

Key Trial Info

Start Date :

June 2 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 21 2021

Estimated Enrollment :

44 Patients enrolled

Trial Details

Trial ID

NCT04358718

Start Date

June 2 2020

End Date

January 21 2021

Last Update

August 9 2021

Active Locations (1)

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1

Renji hospital, School of Medicine, Shanghai Jiaotong University

Shanghai, Shanghai Municipality, China, 200127