Status:
UNKNOWN
DSS's Role in Evaluating the Diagnosis and Treatment System of Ischemic Cardiovascular and Cerebrovascular Diseases
Lead Sponsor:
First Affiliated Hospital Xi'an Jiaotong University
Collaborating Sponsors:
Second Affiliated Hospital of Xi'an Jiaotong University
Shaanxi Provincial People's Hospital
Conditions:
Acute Myocardial Infarction
Acute Ischemic Stroke
Eligibility:
All Genders
18-75 years
Brief Summary
Background: Acute ischemic cardiovascular and cerebrovascular diseases are a kind of diseases with high incidence, rapid progression, poor prognosis and high mortality and disability rate of the circu...
Detailed Description
The experiments as follows: Experiment 1. Observe the dynamic changes of DSS level in acute ischemic cardiovascular and cerebrovascular diseases of different severity. 1. Research object Acute myoca...
Eligibility Criteria
Inclusion
- AMI patients:
- Patients with age between 18 to 75.
- Patients with acute ST-segment elevation myocardial infarction less than 12 hours.
- Without taking DSS and dihydroxyphenylalanine-containing drugs at least one week before admission.
- Acute ischemic stroke patients:
- Patients with age between 18 to 75.
- Patients with acute ischemic stroke less than 12 hours.
- National institutes of health stroke scale (NIHSS) scores ranged from 4 to 20.
- Without taking DSS and dihydroxyphenylalanine-containing drugs at least one week before admission.
- Acute lower limb ischemia patients:
- Patients with age between 18 to 75.
- Patients with typical " 6P " symptom within 14 days: pain, pulselessness, pallor, paresthesia, paralysis and poikilothermia.
- The magnetic resonance imaging and ultrasonography of the lower extremity artery showed that there was ischemia in the lower extremity.
- Without taking DSS and dihydroxyphenylalanine-containing drugs at least one week before admission.
Exclusion
- • Patients with history of cardiogenic shock or cardiopulmonary resuscitation.
- Woman during pregnancy or lactation or anyone with mental disorder.
- A self-identified history of stroke, renal failure, severe arrhythmia or malignant tumor.
- Previous coronary artery bypass graft surgery.
Key Trial Info
Start Date :
July 22 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
1900 Patients enrolled
Trial Details
Trial ID
NCT04359589
Start Date
July 22 2020
End Date
December 31 2021
Last Update
August 26 2021
Active Locations (2)
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1
Shaanxi Provincial People's Hospital
Xi'an, Shaanxi, China, 710000
2
First Affiliated Hospital Xi'an Jiaotong University
Xi'an, Shaanxi, China, 710061