Status:

COMPLETED

DSAP Treatment Comparison: 2% Lovastatin/ 2% Cholesterol vs 2% Lovastatin Alone

Lead Sponsor:

Medical University of South Carolina

Conditions:

Actinic Porokeratosis

Eligibility:

All Genders

18+ years

Phase:

PHASE1

Brief Summary

This study will analyze the effects of topical lovastatin/cholesterol vs topical lovastatin alone in patients with disseminated superficial actinic porokeratosis. Patients will be divided into two gro...

Detailed Description

The purpose of this study is to evaluate the effectiveness of cholesterol/lovastatin versus lovastatin alone to treat porokeratosis. Our working hypothesis is that both topical cholesterol/lovastatin ...

Eligibility Criteria

Inclusion

  • All patients 18 years and older with the diagnosis of disseminated superficial actinic porokeratosis.

Exclusion

  • Patients with allergies or contraindications to lovastatin or cholesterol
  • Female patients currently pregnant or lactating.
  • Female patients with plans to become pregnant.
  • Patients actively taking approved forms of long-term contraception (oral contraceptives, implantable intrauterine devices, or other hormone eluting implants) will be allowed to participate as long as they have no plan to become pregnant during the course of the study. A urine pregnancy test will be administered to these patients to confirm that they can be included in the study.
  • Inability or unwillingness of subject or legal guardian/representative to give informed consent

Key Trial Info

Start Date :

August 24 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 23 2021

Estimated Enrollment :

31 Patients enrolled

Trial Details

Trial ID

NCT04359823

Start Date

August 24 2020

End Date

April 23 2021

Last Update

December 7 2023

Active Locations (1)

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1

Medical University of South Carolina

Charleston, South Carolina, United States, 29425