Status:
UNKNOWN
The Application of Ketamine for Sedation in Patients With Cardiac Arrest - - KetCat (KETamine in Cardiac ArresT) Study
Lead Sponsor:
Fraser Health
Conditions:
Cardiac Arrest, Out-Of-Hospital
Ketamine
Eligibility:
All Genders
19+ years
Phase:
NA
Brief Summary
Recent evidence suggests ketamine may attenuate harmful cellular cascades taking place after brain injury that result in permanent damage. The investigators are interested in researching the applicati...
Eligibility Criteria
Inclusion
- All out-of-hospital cardiac arrests (OHCA) with a "shockable rhythm" (ventricular fibrillation, pulseless ventricular tachycardia) that present to the Royal Columbian Hospital. The patient may be either in active cardiac arrest with shockable rhythm or may have achieved Return of Spontaneous Circulation (ROSC).
- Over 19 years of age
- Patients requiring sedation based on the assessment of the resuscitating physician.
Exclusion
- Any other type of cardiac arrest
- Any history of previous, pre-existing neurological deficit
- Started on Extracorporeal Membrane Oxygenation (ECMO)
- Duration of cardiac arrest without ROSC is greater than 30 consecutive minutes
- Known contraindication or hypersensitivity to ketamine
- Awake patient or no standard sedation or no intubation required
- Inability to obtain deferred consent
- Currently enrolled in any other research study involving drugs or devices
- Patients who are pregnant
- Patients who are prisoners
- Patients residing in Long Term Care (LTC) facilities
Key Trial Info
Start Date :
February 28 2022
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 12 2023
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT04360070
Start Date
February 28 2022
End Date
December 12 2023
Last Update
January 10 2023
Active Locations (1)
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1
Fraser Health Authority - Royal Columbian Hospital
New Westminster, British Columbia, Canada, V3L 3W7