Status:
RECRUITING
Gracie Diet for Gastroesophageal Reflux Disease
Lead Sponsor:
Johns Hopkins University
Conditions:
Gastroesophageal Reflux
GERD
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The goal of this clinical trial is to learn if dietary changes can help improve gastroesophageal reflux disease (GERD) symptoms. The main question\[s\] it aims to answer whether the Gracie Diet is an ...
Detailed Description
GERD, is a common and chronic world-wide disease. Cardinal symptoms of this condition are heartburn-regurgitation, and sometimes with extra-intestinal symptoms that can affect patients' quality of lif...
Eligibility Criteria
Inclusion
- Age 18 years or older at registration.
- Patients with ongoing symptoms of GERD: heartburn (pyrosis) mid-sternal chest pain, regurgitation of fluid or food, development of esophageal inflammation that may lead to swallowing dysfunction, or extraesophageal manifestations (i.e. cough, bronchospasms, and hoarseness).
- Use of one of the following PPI medications: omeprazole, lansoprazole, pantoprazole, rabeprazole, esomeprazole or dexlansoprazole. And/or use of one of the following H2 blockers medications as well: famotidine, cimetidine, ranitidine or nizatidine.
- Willing to comply with the Gracie diet regimen
Exclusion
- Age \< than 18 years.
- Patients unable to speak English.
- Pregnancy or nursing.
- Complicated oropharyngeal dysphagia or other condition with risk for aspiration from oral ingestion.
- Exclusion of other causes of symptoms as mechanical gastrointestinal obstruction, Barrett's esophagus and cancer of the esophagus by standard radiographic or endoscopic test evidenced in the medical record chart.
- A prior surgery of the upper gastrointestinal tract.
- Failure to give informed consent.
- Any other condition, which in the opinion of the investigator would impede compliance or hinder the completion of the study.
Key Trial Info
Start Date :
November 13 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2025
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04360252
Start Date
November 13 2020
End Date
December 1 2025
Last Update
January 17 2025
Active Locations (1)
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1
Johns Hopkins Bayview Medical Center
Baltimore, Maryland, United States, 21224