Status:
COMPLETED
PEEP Incremental and Decremental Alveolar Recruitment of Critically Ill Corona Virus Disease-19 (COVID-19) Patients
Lead Sponsor:
Szeged University
Collaborating Sponsors:
Hochschule Furtwangen University
Budapest University of Technology and Economics
Conditions:
COVID-19
Virus; Pneumonia
Eligibility:
All Genders
18-99 years
Phase:
NA
Brief Summary
COVID-19 originated from Severe Acut Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection leads to critical condition due to hypoxemic respiratory failure with the background of viral pneumonia. ...
Detailed Description
COVID-19 originated from Severe Acut Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection leads to critical condition in 5% of the cases due to hypoxemic respiratory failure with the background o...
Eligibility Criteria
Inclusion
- SARS-CoV-2 positivity confirmed by polymerase chain reaction
- orotracheally intubated patients
- pressure control ventilation mode
- sedation level of minimum -4 on the Richmond Agitation Sedation Scale (RASS)
Exclusion
- age under 18
- pregnancy
- pulmonectomy, lung resection in the past medical history
- clinically end stage chronic obstructive pulmonary disease
- sever hemodynamic instability (vasopressor refractory shock)
- sever bullous emphysema and/or spontaneous pneumothorax in the past medical history chest drainage in situ due to pneumothorax and/or bronchopleural fistula
Key Trial Info
Start Date :
May 6 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2020
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT04360837
Start Date
May 6 2020
End Date
July 1 2020
Last Update
February 15 2022
Active Locations (1)
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1
University of Szeged
Szeged, Hungary, 6725