Status:
COMPLETED
Lipid Peroxidation and Options Antioxidant Therapy for Secondary Lymphedema of the Lower Extremities
Lead Sponsor:
Ryazan State Medical University
Conditions:
Lower Extremity Lymphedema
Eligibility:
All Genders
Phase:
PHASE4
Brief Summary
A single-center, open, prospective, randomized, controlled clinical trial will include 120 patients with lower limb lymphedema who undergo treatment in an office-based vascular lab at the Ryazan regio...
Detailed Description
Research methods: 1. Physical examination; 2. peripheral blood sampling (assessment of the concentration of the markers of endothelial dysfunction, including malondialdehyde (MDA), superoxide dismuta...
Eligibility Criteria
Inclusion
- Secondary lymphedema of the lower extremities
- Signed Informed Consent Form
Exclusion
- varicose veins of the lower extremities,
- deep vein thrombosis,
- post-thrombotic disease,
- obliterating
- atherosclerosis of the lower limb arteries,
- pregnancy,
- lactation,
- cancer,
- acute violation of cerebral circulation in the anamnesis,
- trophic lesions of the skin of the lower extremities,
- diabetes mellitus
- an infectious disease with a history of three months prior to inclusion in the study,
- heart failure,
- kidney failure,
- pulmonary insufficiency.
Key Trial Info
Start Date :
September 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 3 2022
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04360889
Start Date
September 1 2019
End Date
August 3 2022
Last Update
August 4 2022
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Ryazan State Medical University
Ryazan, Russia, 390026