Status:

TERMINATED

Neurodegeneration Markers and Neurological Course in Severe Covid-19 Infection

Lead Sponsor:

Centre Hospitalier de PAU

Conditions:

COVID-19 Infection

Encephalitis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Emergence of Covid-19 virus is associated with high frequency of extremely severe clinical pictures, with minor signs of CNS impairment (e.g. anosmia, headache). Since neurotropism is a common feature...

Detailed Description

In animals, coronavirus infection is commonly associated with CNS involvement: epilepsy and ataxia are observed during Feline Infectious Peritonitis (FIP) and virus is recovered in CSF, CNS is involv...

Eligibility Criteria

Inclusion

  • Infection with Covid-19 (proven or probable) AND
  • possible encephalitis (at least confusion, epilepsy) OR
  • clinical severity requiring invasive ventilation.

Exclusion

  • brain stroke
  • minor CNS dysfunction (isolated smell loss or headache),
  • absence of Covid infection.

Key Trial Info

Start Date :

May 19 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 25 2020

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT04361344

Start Date

May 19 2020

End Date

October 25 2020

Last Update

February 4 2021

Active Locations (1)

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1

CH de Pau

Pau, France, 64046