Status:
COMPLETED
COVID-19 Infection: Exploration of Respiratory Control Center Abnormalities
Lead Sponsor:
Assistance Publique - Hôpitaux de Paris
Conditions:
Covid19
Neurological Complication
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of the present study is to determine whether there is a decrease in the emotional response to experimental induction of dyspnea by hypoxic stimulation in subjects with a "neurological" for...
Detailed Description
SARS CoV-2 infection causes lung damage that can be severe enough to require artificial ventilation. Clinicians taking care of these patients are surprised by the scant respiratory sensations and emot...
Eligibility Criteria
Inclusion
- \- adult (≥ 18 years old, unprotected);
- for COVID-19 + patients: COVID-19 + diagnosis; with quantitative or qualitative anomalies in taste and smell; first symptoms appeared in less than 21 days
- for healthy subjects: have never presented any sign of COVID ; confirmed by recent negative serology
- understanding French;
- affiliated to social security;
- having a BMI between 20 and 30;
- preferably non-smokers and in the event of recruitment difficulties, smokers but with smoking \<5 packs - year
- signature of the informed consent form
Exclusion
- respiratory signs or symptoms (rhinitis, cough, shortness of breath at rest);
- temperature above 37.5 ° C;
- existence of a chronic respiratory pathology (including asthma and COPD in the first row);
- pregnant women ;
- protected minors and adults, persons deprived of their liberty;
- not affiliated to a social security (including AME);
- contraindication to MRI (pace maker, intracranial implants, etc.).
Key Trial Info
Start Date :
April 27 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 11 2021
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04363749
Start Date
April 27 2020
End Date
January 11 2021
Last Update
August 30 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Département R3S, hôpital de la pitié-salpêtrière
Paris, France, 75013