Status:

COMPLETED

IM Neostigmine for Accelerating Bladder Emptying After CS by Spinal Anesthesia

Lead Sponsor:

Mansoura University

Conditions:

Cesarean Section Complications

Eligibility:

FEMALE

20-35 years

Phase:

PHASE4

Brief Summary

The aim of this study is to assess the efficacy of IM neostigmine (0.5 mg) for acceleration of bladder evacuation and prevention of postoperative urine retention following cesarean delivery carried ou...

Detailed Description

Following cesarean delivery, women will receive either 0.5 mg IM neostigmine (study group) or IM NaCl 0.9% (control group). Bladder ultrasonography will be done every hour until spontaneous voiding oc...

Eligibility Criteria

Inclusion

  • Pregnant women undergoing elective cesarean deliver under spinal anesthesia.

Exclusion

  • The age of the patient is more than 35 years of less than 20 years.
  • The body mass index of the patient is more than 35 kg/m2 or her height is more than 180 cm or less than 150 cm.
  • Multiple gestation.
  • The patient is in active labor.
  • Vaginal bleeding, placenta previa or abruption of the placenta.
  • Presence of fetal distress.
  • Urinary symptoms.
  • Medical disorders co-existing with or complicating pregnancy.
  • Contraindications for or history of adverse reaction of Neostigmine.
  • Contraindication for spinal anesthesia.
  • Refusal of the patient to receive spinal anesthesia.
  • Intraoperative significant hemorrhage.
  • Duration of the operation is more than one hour.
  • Occurrence of postoperative complications as eclampsia.

Key Trial Info

Start Date :

August 5 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

October 26 2021

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04364607

Start Date

August 5 2020

End Date

October 26 2021

Last Update

June 7 2023

Active Locations (1)

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Mansoura University Hospital

Al Mansurah, Dakahlia Governorate, Egypt, 35111