Status:
WITHDRAWN
OUTpatient Treatment of COVID-19 in Patients With Risk Factor for Poor Outcome
Lead Sponsor:
Fondation Hôpital Saint-Joseph
Conditions:
COVID
Eligibility:
All Genders
50+ years
Phase:
PHASE3
Brief Summary
COVID-19 is a respiratory disease due to a novel coronavirus (SARS-CoV-2) that causes substantial morbidity and mortality. To date, no treatment has been proved to be effective in COVID-19. Elderly pa...
Detailed Description
The investigators make the hypothesis that an early outpatient treatment of COVID among patient with respiratory symptoms and risk factors for poor outcome can improve the prognosis of these patient a...
Eligibility Criteria
Inclusion
- Either patients over 50 years of age with at least one comorbidity (hypertension, diabetes, obesity, cancer, chronic renal disease, immunodeficiency) OR patients over 70 years of age with or without comorbidity
- Laboratory (PCR-) proved infection by COVID-19 or radiological sign highly suggestive of COVID-19
- Respiratory symptoms (cough, chest discomfort, dyspnea)
- Affiliation to the social security network
- Able to understand and sign a written informed consent form
Exclusion
- Need for hospitalization according to updated French guidelines (ministère de la santé\_04/04/2020)
- Patient in long-term care facility
- Patient without concern confirmation of COVID-19 by laboratory (PCR swab) test or chest CT
- Known hypersensitivity or contra-indication to the 3 experimental treatments (azithromycin, hydroxychloroquine, lopinavir/ritonavir).
- Any reason making follow up of the patient impossible during the study period.
Key Trial Info
Start Date :
May 7 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 19 2021
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04365582
Start Date
May 7 2020
End Date
April 19 2021
Last Update
April 27 2021
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.