Status:

TERMINATED

A Randomized Control Trial Comparing Analgesic Benefits of Ultrasound-guided Single vs Continuous Quadratus Lumborum Blocks (QLB)vs Intrathecal Morphine(ITM) for Post Cesarean Section Pain

Lead Sponsor:

The University of Texas Health Science Center, Houston

Conditions:

Pain, Postoperative

Eligibility:

FEMALE

18+ years

Phase:

PHASE4

Brief Summary

the purpose of this study is to compare opioid consumption in morphine equivalents between the groups that received postoperative analgesia with intrathecal morphine versus US guided QL blocks versus ...

Eligibility Criteria

Inclusion

  • Elective C section via Pfannenstiel incision
  • Living singleton pregnancy
  • Gestation week at least 37 weeks
  • American Society of Anesthesiologists (ASA) status 1, 2 and 3
  • Primary and secondary C sections

Exclusion

  • Chronic pain
  • Opioid tolerant patients
  • Allergy to drugs used in the study.
  • Cognitive dysfunction
  • BMI \> 40
  • Coagulation disorder
  • Local infection
  • Inability to tolerate oral medication
  • Previous intra-abdominal surgery
  • Patients who will receive a combined spinal epidural for their C section
  • Local anesthetics injected at any other fascial plane except the QLB plane (for e.g.- local wound infiltration by surgeon)
  • Patients who received sedation or general anesthesia during their C section (midazolam, ketamine, fentanyl, propofol, hydromorphone)

Key Trial Info

Start Date :

May 22 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 29 2020

Estimated Enrollment :

3 Patients enrolled

Trial Details

Trial ID

NCT04368364

Start Date

May 22 2020

End Date

June 29 2020

Last Update

May 16 2022

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Memorial Hermann Hospital TMC

Houston, Texas, United States, 77030

2

The University of Texas Health Science Center at Houston

Houston, Texas, United States, 77030