Status:

UNKNOWN

DSA Risk Factors in MMF-based Immunosuppressed Post-transplanted Patients

Lead Sponsor:

First Affiliated Hospital Xi'an Jiaotong University

Conditions:

Antibody-mediated Rejection

Eligibility:

All Genders

18-65 years

Brief Summary

Kidney transplantation is the best therapy method for patients with uremia. The main factors affecting the long-term survival of the graft were chronic antibody-mediated rejection and the death of the...

Eligibility Criteria

Inclusion

  • years 18-65
  • single organ transplantation
  • first time to accept kidney transplantation
  • Triple immunosuppression protocol based on MMF, tacrolimus and glucocorticoid
  • PRA negative before transplantation
  • not pregnant for female

Exclusion

  • Not accept MMF
  • multi-organ transplantation
  • pregnancy or lactation period female
  • mental illness
  • past tumor, peptic ulcer, severe cardiopulmonary disease, active liver disease history
  • Cannot regular follow up

Key Trial Info

Start Date :

January 22 2021

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

December 1 2023

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT04368962

Start Date

January 22 2021

End Date

December 1 2023

Last Update

May 27 2022

Active Locations (1)

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1

The First Affiliated Hospital of Xi'an Jiaotong University

Xi'an, Shaanxi, China, 710061