Status:
COMPLETED
Prevention of Colorectal Cancer Through Multiomics Blood Testing
Lead Sponsor:
Freenome Holdings Inc.
Conditions:
Colon Cancer
Rectal Cancer
Eligibility:
All Genders
45-85 years
Brief Summary
The PREEMPT CRC study is a prospective multi-center observational study to validate a blood-based test for the early detection of colorectal cancer by collecting blood samples from average-risk partic...
Detailed Description
Freenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early. The purpose of this prospective multi-center...
Eligibility Criteria
Inclusion
- Key Inclusion Criteria
- 45-85 years of age
- Willing to undergo a standard-of-care screening colonoscopy
- Able and willing to provide a blood sample
- Able and willing to sign informed consent
- Key Exclusion Criteria
- Known hereditary gastrointestinal cancer syndrome (for example, hereditary non-polyposis CRC syndrome (HNPCC) or Lynch syndrome, or familial adenomatous polyposis (FAP)
- Personal history 2.1 CRC or colorectal adenoma 2.2 Inflammatory bowel disease (IBD), including chronic ulcerative colitis (CUC) and crohn's disease (CD) 2.3 Colonoscopy in the 9 years preceding enrollment 2.4 Stool DNA testing in the 2 years preceding enrollment 2.5 Symptoms of lower gastrointestinal tract disease warranting colonoscopic evaluation
- A medical condition which, in the opinion of the Investigator, should preclude enrollment in the study
- Participated or currently participating in a clinical research study in which an experimental medication has been administered during the 60 days up to and including the date of providing informed consent or may be administered through the time of the colonoscopy
Exclusion
Key Trial Info
Start Date :
May 20 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 29 2024
Estimated Enrollment :
48995 Patients enrolled
Trial Details
Trial ID
NCT04369053
Start Date
May 20 2020
End Date
February 29 2024
Last Update
December 26 2025
Active Locations (148)
Enter a location and click search to find clinical trials sorted by distance.
1
Central Alabama Research
Birmingham, Alabama, United States, 35209
2
Alabama Oncology
Birmingham, Alabama, United States, 35243
3
Clinical Research Associates
Huntsville, Alabama, United States, 35801
4
Del Sol Research Management
Chandler, Arizona, United States, 85224