Status:

COMPLETED

Transcranial Electrical Stimulation With Special Waveform for Upper Extremity Rehabilitation for Patients With Stroke

Lead Sponsor:

Taipei Medical University

Collaborating Sponsors:

Ministry of Science and Technology, Taiwan

Conditions:

Stroke

Eligibility:

All Genders

20+ years

Phase:

NA

Brief Summary

Transcranial electrical stimulation (tCES) is contemporarily important issues in the advanced rehabilitation medicine. tCES can selectively change the excitability of regional cortex with non-invansiv...

Detailed Description

Transcranial direct current stimulation (tDCS) and intermittent theta burst stimulation (iTBS) were both demonstrated to have therapeutic potentials to rapidly induce neuroplastic effects in various r...

Eligibility Criteria

Inclusion

  • Age ≥ 20 years.
  • Unilateral cerebral stroke with hemiplegia in Brunnstrom stage III-V.
  • 6 months to 5 years after stroke.
  • Adequate understanding of verbal/written information and physically able to complete the motor learning of functional tasks with the affected hand.

Exclusion

  • Extremely sensitive to electrical stimulation and cannot tolerate it.
  • Contracture on upper extremities, and limitation in joint range of motion.
  • The muscle tone was severe spasticity.
  • Ossification or inflammation in muscle tissue.
  • A history of cardiopulmonary disease or arrhythmia.
  • With implantable medical electronic devices, like pacemaker.
  • Pressure sores or wounds on the skin of head and upper extremities.
  • Metal implants in the head (neck).
  • Severe cognitive or psychiatric disorders, such as schizophrenia or dissociative identity disorder.
  • A history of seizure or other brain pathology.
  • Brain surgery or severe brain trauma.
  • Drug or alcohol abuse.
  • Malignant neoplasm or rheumatism disorder, like SLE, RA, or AS.

Key Trial Info

Start Date :

March 2 2017

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 30 2020

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT04369235

Start Date

March 2 2017

End Date

April 30 2020

Last Update

April 15 2021

Active Locations (1)

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Taipei Medical University

Taipei, Taiwan