Status:

COMPLETED

Avdoralimab an Anti-C5aR Antibody, in Patients With COVID-19 Severe Pneumonia ( FORCE )

Lead Sponsor:

Assistance Publique Hopitaux De Marseille

Collaborating Sponsors:

Innate Pharma

Conditions:

COVID

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

The primary objective of this trial is to improve the proportion of COVID-19 patients with severe pneumonia who no longer need to be hospitalized, and to reduce the need for and duration of mechanical...

Eligibility Criteria

Inclusion

  • COVID-19 severe pneumonia patients need for oxygen therapy ≥ 5 l/min or high-flow oxygen therapy
  • COVID-19 related Acute Respiratory Distress Syndrome (ARDS) requiring mechanical ventilation

Exclusion

  • Pregnant woman
  • Uncontrolled sepsis of bacterial or fungal origin

Key Trial Info

Start Date :

April 27 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 30 2021

Estimated Enrollment :

208 Patients enrolled

Trial Details

Trial ID

NCT04371367

Start Date

April 27 2020

End Date

March 30 2021

Last Update

May 27 2021

Active Locations (1)

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Assistance Publique Hôpitaux de Marseille

Marseille, France, 13354