Status:
COMPLETED
DNA Methylation Analysis in Acute Coronary Syndrome and Atrial Fibrillation: DIANA Clinical Trial
Lead Sponsor:
University of Campania Luigi Vanvitelli
Conditions:
Coronary Artery Disease
Acute Coronary Syndrome
Eligibility:
All Genders
40+ years
Brief Summary
Although epigenetics has been identified as one of the most relevant pathophysiological components in the development of cardiovascular diseases, there is still considerable difficulty in finding mark...
Detailed Description
Study population will include 20 healthy controls admitted to electrocardiographic control without further cardiological, electrocardiographic and clinical evidence of cardiac pathologies, 20 patients...
Eligibility Criteria
Inclusion
- Patients with clinically diagnosed of AF and ACS, in particular unstable angina pectoris (UAP), acute myocardial infarction without ST elevation (NSTEMI) and acute myocardial infarction with ST elevation (STEMI), based on clinical history, symptoms, ECG, biomarkers of damage cardiac, coronary angiography, risk factors and/or other clinical tests according to the guidelines for UAP/ NSTEMI and STEMI
Exclusion
- Patients with known history of cancer, malignancy disorders, active infections, and chronic or immune-mediated diseases.
Key Trial Info
Start Date :
March 20 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 20 2022
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04371809
Start Date
March 20 2019
End Date
March 20 2022
Last Update
July 19 2022
Active Locations (1)
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1
University of Campania Luigi Vanvitelli, Cardarelli Hospital
Naples, Italy, 80138