Status:
COMPLETED
Driving Pressure in Laparoscopic Surgery
Lead Sponsor:
Capital Medical University
Conditions:
Laparoscopy
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
The effect of driving pressure (DP)-guided positive end expiratory pressure (PEEP) on early postoperative pulmonary ventilation is to be determined for patients undergoing laparoscopic surgery. Patien...
Detailed Description
After screened for preoperative risk factors, 48 patients undergoing elective laparoscopic surgery and planned to be extubated in the operating room are randomly assigned to two groups: (1) PEEP = 5cm...
Eligibility Criteria
Inclusion
- Informed consent has been obtained
- Elective laparoscopic surgery with Trendelenburg position
- Expected ventilation duration \> 2 hours
- Scheduled to be extubated in the operation
Exclusion
- Mechanical ventilation of \> 1 hour within the last 2 weeks before surgery
- Body mass index ≥ 35 kg/m2
- Acute respiratory failure (pneumonia, acute lung injury or acute respiratory distress syndrome)
- Emergency surgery
- Severe cardiac disease
- Progressive neuromuscular illness
- Pregnancy
- Refusal to participate
- Contradicted to EIT scan
Key Trial Info
Start Date :
May 19 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 1 2021
Estimated Enrollment :
57 Patients enrolled
Trial Details
Trial ID
NCT04374162
Start Date
May 19 2020
End Date
July 1 2021
Last Update
July 6 2021
Active Locations (1)
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1
Department of Anesthesiology,Beijing Tiantan Hospital, Capital Medical University
Beijing, Beijing Municipality, China, 100070