Status:
COMPLETED
Effects of Acute Intake of Flavanols on Cerebral Oxygenation and Cognition in Young Male Adults
Lead Sponsor:
University of Birmingham
Collaborating Sponsors:
University of Illinois at Urbana-Champaign
Conditions:
Healthy
Eligibility:
MALE
18-45 years
Phase:
NA
Brief Summary
The study evaluates the impact of one acute dose of cocoa flavanols on brain oxygenation during a hypercapnia challenge, as well as impact on cognitive performance in young healthy males. It further a...
Detailed Description
Cocoa flavanols have been shown to be protective against vascular disease in humans, as evidenced by improvements in peripheral endothelial function (as measured by brachial Flow-mediated dilatation, ...
Eligibility Criteria
Inclusion
- Male
- 18-45 years old
Exclusion
- smokers
- hypertensive
- with history of cerebrovascular, cardiovascular or respiratory disease
- allergies or intolerances to ingredients present in cocoa powders
- taking long-term medication (e.g., hyperlipidaemia)
- on antibiotics for the previous 3 months before enrollment
- suffering from blood-clotting disorders
- known infections at the time of the study
- on a weight-reducing regimen
Key Trial Info
Start Date :
October 2 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 12 2018
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT04374409
Start Date
October 2 2018
End Date
December 12 2018
Last Update
May 11 2020
Active Locations (1)
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1
School of Sport, Exercise & Rehabilitation Sciences, University of Birmingham
Birmingham, United Kingdom, B15 2TT