Status:
UNKNOWN
The Effectiveness of Hyperbaric Oxygen Therapy on Pneumonia Complicating Stroke
Lead Sponsor:
Ya Zhang
Conditions:
Hyperbaric Oxygen Therapy
Stroke
Eligibility:
All Genders
Phase:
NA
Brief Summary
To investigate the evidence for the integration of hyperbaric oxygen therapy (HBOT) as part of interdisciplinary stroke rehabilitation.
Detailed Description
Pneumonia complicating stroke is very difficult to manage and has a very poor prognosis, leading to a significantly higher risk of death. Oral opportunistic pathogens have been reported to be associat...
Eligibility Criteria
Inclusion
- New stroke events within 1-3 months (confirmed by CT and MRI)
- Moderate to severe disability (Barthel Index \< 70)
- The patient is conscious, breathing autonomously, not undergoing tracheotomy or tracheal intubation for ventilator-assisted respiration
- No concurrent lower respiratory infections and other lung diseases
- The condition is relatively stable
- Cognitive function is normal to moderately impaired (Mini-Physical State Exchange, MMSE score\>18)
- The Gugging Swallowing Screen (GUSS) shows swallowing difficulties
- No systemic and local use of antibiotic-containing mouthwash
Exclusion
- A mild disability (Barthel Index \> 70)
- The swallowing function is normal
- Indwelling nasogastric feeding tube
- The neurological status of the patient was significantly dynamically altered (significantly improved or worsened) in the short term prior to inclusion in the trial
- The patient had been treated with hyperbaric oxygen for other indications
- Had a chest condition and cannot withstand the pressure changes caused by hyperbaric oxygen therapy
- Have an inner ear disease
- Claustrophobia
- Communication barriers and inability to give informed consent
Key Trial Info
Start Date :
June 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2021
Estimated Enrollment :
168 Patients enrolled
Trial Details
Trial ID
NCT04376359
Start Date
June 1 2021
End Date
August 1 2021
Last Update
January 14 2021
Active Locations (1)
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1
The Second People's Hospital of Hefei
Hefei, Anhui, China, 230000