Status:

UNKNOWN

Exchange Transfusion Versus Plasma From Convalescent Patients With Methylene Blue in Patients With COVID-19

Lead Sponsor:

Ain Shams University

Conditions:

COVID-19

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

The aim of this project is to introduce way for treatment of patients with severe COVID-19 disease with respiratory complications.

Detailed Description

Study Tools AND/ OR procedure The patients were subjected to the following: Clinical parameters: Complete history taking and thorough clinical examination 1. Laboratory parameters: 2. CBC with dif...

Eligibility Criteria

Inclusion

  • Adult patients are 18 years old or above.
  • Inpatients diagnosed as severe COVID - 19 disease according to WHO criteria.
  • CT chest with extensive lung disease (ground-glass and consolidative pulmonary opacities).
  • O2 saturation less than 93% resting.
  • Respiratory rate equal or more than 30 per minute.

Exclusion

  • Patients with pregnancy and lactation.
  • Renal failure and heart failure.
  • Contraindication for plasma or blood transfusion.

Key Trial Info

Start Date :

May 20 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2020

Estimated Enrollment :

15 Patients enrolled

Trial Details

Trial ID

NCT04376788

Start Date

May 20 2020

End Date

September 1 2020

Last Update

July 9 2020

Active Locations (1)

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1

Ain Shams University

Cairo, Egypt, 11556