Status:

UNKNOWN

Improvement of Pigmented Skin Lesions in Patients With Mastocytosis After Performing 2 Sessions of Pigment Laser

Lead Sponsor:

University Hospital, Toulouse

Conditions:

Cutaneous Mastocytosis

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Cutaneous mastocytosis can be isolated or associated with systemic involvement. Urticaria pigmentosa affects around 80 to 85% of adult patients with cutaneous mastocytosis. It is also frequently prese...

Detailed Description

Cutaneous mastocytosis can be isolated or associated with systemic involvement. Urticaria pigmentosa affects around 80 to 85% of adult patients with cutaneous mastocytosis. It is also very frequently ...

Eligibility Criteria

Inclusion

  • Patient with mastocytosis (diagnosis confirmed clinically according to international criteria)
  • Patient with pigmented skin lesions, of moderate to very severe severity (by comparison with a 4-point photographic scale: light, moderate, severe and very severe)
  • Major patient aged ≥ 18 years.
  • Patient with social security coverage
  • Patient having given written, free and informed consent to participate in the study

Exclusion

  • Patients with mastocytosis, without skin lesions
  • Patient with pigmented skin lesions, only of mild severity (by comparison with a 4-point photographic scale: mild, moderate, severe and very severe)
  • Patient with another cutaneous mastocytosis phenotype
  • Patient treated by a treatment known as a cytoreductive for mastocytosis: alpha interferon, cladribine, imatinib, midostaurin or any cytoreductive treatment being evaluated by clinical trial in mastocytosis
  • Patient under guardianship, or under curatorship, or not fluent in the French language or unable to understand and complete the study questionnaires
  • pregnant or breastfeeding women
  • Patients with tanned skin following photoexposure within 3 weeks of starting the study

Key Trial Info

Start Date :

September 14 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

June 1 2022

Estimated Enrollment :

34 Patients enrolled

Trial Details

Trial ID

NCT04377828

Start Date

September 14 2020

End Date

June 1 2022

Last Update

September 25 2020

Active Locations (1)

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1

Larrey Hospital - Toulouse University Hospital

Toulouse, France, 31059