Status:

TERMINATED

Study in Parkinson's Disease Patients With Dyskinesia With Combinations of JM-010 and Its Individual Components

Lead Sponsor:

Bukwang Pharmaceutical

Conditions:

Dyskinesias

Parkinson Disease

Eligibility:

All Genders

18-85 years

Phase:

PHASE2

Brief Summary

This is a two-part, double-blind, placebo-controlled, randomized, multicenter Phase 2 clinical trial of JM-010 in patients with Parkinson's Disease.

Detailed Description

This is a two-part, Phase 2, double-blind, placebo-controlled, randomized, multicentre study. Subjects with a diagnosis of PD and dyskinesias in PD will complete a Screening Visit to assess eligibili...

Eligibility Criteria

Inclusion

  • Is able to read, understand, and provide written, dated informed consent prior to Screening Visit.
  • Is male or female, between 18 and 85 years of age at Screening Visit.
  • Is diagnosed with idiopathic PD that meets UK Parkinson's Disease Society (UKPDS) Brain Bank Clinical Diagnostic Criteria
  • Has experienced dyskinesia
  • Has stable peak-effect dyskinesia
  • Has more than one hour of "ON" time with troublesome dyskinesia

Exclusion

  • Has undergone surgery for the treatment of PD
  • Has a current diagnosis of Substance Use
  • Has psychiatric diagnosis of acute psychotic disorder or other psychiatric diagnoses
  • Has current seizure disorders requiring treatment with anticonvulsants.
  • Other criteria related to other medical conditions to be referred to the protocol.

Key Trial Info

Start Date :

April 28 2021

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 14 2024

Estimated Enrollment :

41 Patients enrolled

Trial Details

Trial ID

NCT04377945

Start Date

April 28 2021

End Date

February 14 2024

Last Update

June 17 2024

Active Locations (2)

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Page 1 of 1 (2 locations)

1

Bukwang Investigator site

Miami, Florida, United States, 33165

2

Bukwang Investigator site

Detroit, Michigan, United States, 48201