Status:

UNKNOWN

Higher Versus Standard Dose of Amoxicillin-clavulanate in Pediatric PBB

Lead Sponsor:

Second Affiliated Hospital of Wenzhou Medical University

Conditions:

Protracted Bacterial Bronchitis

Eligibility:

All Genders

2-6 years

Phase:

NA

Brief Summary

Chronic wet cough is one of the most common symptoms of respiratory diseases in children. Protracted bacterial bronchitis (protracted bacterial bronchitis, PBB) is the most common cause of chronic wet...

Detailed Description

Chronic cough is one of the common reasons for children seeking medical treatment. In children, chronic cough is associated with impaired quality of life, multiple doctor visits, and adverse effects f...

Eligibility Criteria

Inclusion

  • Children diagnosed with first-onset PBB
  • Subjects and their guardians agree to participate in the study and sign an informed consent

Exclusion

  • Seriously delayed development of the nervous system;
  • With severe underlying diseases: such as severe neuromuscular diseases, immunodeficiency, malnutrition, heart diseases, congenital respiratory system malformation, and other diseases of the heart, brain, liver, kidney and blood system;
  • Other diseases that can cause chronic wet cough, including chronic rhinitis, sinusitis, interstitial lung disease, and clinical suspicion of bronchiectasis;
  • With poor compliance and expected difficulty in completing the study;
  • Other conditions considered inappropriate by the researcher.

Key Trial Info

Start Date :

May 1 2020

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 1 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04378231

Start Date

May 1 2020

End Date

July 1 2022

Last Update

May 7 2020

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