Status:
COMPLETED
Aerobic Exercise and Brain Health in Parkinson's
Lead Sponsor:
University of Aarhus
Conditions:
Parkinson Disease
Eligibility:
All Genders
40-100 years
Phase:
NA
Brief Summary
The purpose of the project is to investigate how moderate to high intensity aerobic exercise affects brain health in patients with Parkinson's disease. Assessments include MRI, blood markers, cognitio...
Detailed Description
Background: No approved medical treatments preventing, delaying or stopping Parkinson's disease (PD) exist, making identification of interventions having this potential a major priority. Exercise stud...
Eligibility Criteria
Inclusion
- Informed consent
- Age ≥ 40 years
- Idiopathic PD diagnosis (within the previous five years)
- Patients in symptomatic therapy / not in therapy. Patients who are not already taking medication are not expected to need medication within 6 months of inclusion (in case of drug startup, this is noted)
- Hoehn \& Yahr ≤ 3
- Ability to transport oneself to and from exercise and testing
Exclusion
- Alcohol abuse, depression, pacemaker
- Comorbidity/competing (neurological) disorder preventing participation in the intervention
- Pregnancy
- Metallic implants that prevent MRI.
- Expected exercise adherence below 85% of all planned sessions.
- Systematic moderate-high-level AE more than twice per week prior to start-up in the project
Key Trial Info
Start Date :
March 1 2021
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2023
Estimated Enrollment :
70 Patients enrolled
Trial Details
Trial ID
NCT04379778
Start Date
March 1 2021
End Date
October 1 2023
Last Update
May 8 2024
Active Locations (1)
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1
Sport Science, Department of Public Health, Aarhus University
Aarhus, Aarhus C, Denmark, 8000