Status:
WITHDRAWN
Cycling Duration and Bone Markers in in Active Young Adults
Lead Sponsor:
Brock University
Collaborating Sponsors:
Natural Sciences and Engineering Research Council, Canada
Conditions:
Bone Loss
Energy Supply; Deficiency
Eligibility:
MALE
20-30 years
Phase:
NA
Brief Summary
Exercise is an important factor in bone health. Sclerostin is one of the key molecules involved in bone response to mechanical loading. In particular, sclerostin decreases bone formation directly thro...
Detailed Description
Introduction: Exercise has been shown to positively benefit bone health. It's well documented that an acute bout of weight bearing, high load and dynamic strain on the skeleton mobilizes markers of b...
Eligibility Criteria
Inclusion
- Caucasian males,
- aged 20 to 30 years,
- healthy (not suffering from asthma),
- of normal weight (BMI: 18.5 - 25 kg/m2),
- recreationally active (i.e., regularly exercise 3-6 times per week, including 3 times of aerobic exercise over 45 min per session).
Exclusion
- with no fracture over the last year,
- not taking any medication related to a chronic condition or bone health including food/nutritional supplements (e.g. protein, vitamin D, calcium),
- non-smokers,
- with no injuries or chronic conditions in which exercise may pose a risk (e.g., ACL or knee/hip/lower back injuries, arthritis, osteoporosis, neuromuscular diseases),
- currently not on a low carbohydrate or ketogenic diet.
Key Trial Info
Start Date :
September 20 2023
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 29 2023
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04380155
Start Date
September 20 2023
End Date
October 29 2023
Last Update
October 31 2023
Active Locations (1)
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1
Brock University
Saint Catharines, Ontario, Canada, L2S 3A1