Status:

UNKNOWN

Transcutaneous Vagal Stimulation in Knee Osteoarthritis

Lead Sponsor:

Universidad de La Frontera

Conditions:

Osteoarthritis, Knee

Eligibility:

All Genders

55+ years

Phase:

NA

Brief Summary

This study will evaluate the efficacy of Transcutaneous Vagal Stimulation in people whit knee osteoarthritis.

Detailed Description

Current treatments for knee osteoarthritis (KOA) are partially effective. It is, therefore, necessary to find new strategies that can complement the existing ones. In this scenario, transcutaneous vag...

Eligibility Criteria

Inclusion

  • Women and men aged 55 and over;
  • Medical diagnosis of osteoarthritis of the knee according to the criteria of the American College of Rheumatologists;
  • Chronic pain (i.e., 3 months or more)
  • Average pain of the last seven days among 30 mm and 80 mm on the Visual Analogue Scale;
  • Walking without technical aids or knee brace;
  • Availability to attend an exercise program three times a week for four weeks;
  • Access to communication via telephone;
  • Agree to participate in the study by signing an informed consent form.

Exclusion

  • Presence of the following symptoms and signs: Fever or chills, large effusions, paresthesias or paresis of the lower limb;
  • Presence of medically diagnosed psychiatric or neurological diseases (cognitive impairment, Alzheimer's, Parkinson's, epilepsy, moderate or severe depression, bipolar disorders, obsessive-compulsive disorder, etc.)
  • Neuromuscular or cardiac disorders (i.e., arrhythmia, conduction cardiac block), stroke, generalised rheumatology, dia-betes mellitus II, morbid obesity (i.e., equal to or greater than III);
  • Medical contraindication of physical exercise;
  • Joint infiltration or lower limb surgery in the previous 6 months;
  • Surgery is planned for the next 6 months;
  • Take strong regular two or more kinds of medication;
  • Conditions that affect the lower limb and/or limit its functional capacity, such as previous fractures in the area, deformity, joint replacement, tibial osteotomy;
  • Participation in exercise programs in the last nine months;
  • Inability to follow instructions.

Key Trial Info

Start Date :

March 1 2023

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

March 1 2024

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04381624

Start Date

March 1 2023

End Date

March 1 2024

Last Update

December 13 2022

Active Locations (1)

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1

Universidad de La Frontera

Temuco, La Araucania, Chile, 4781176