Status:

COMPLETED

Impact of Ketogenic Diets in Preventing Relapse in Obesity Management

Lead Sponsor:

Norwegian University of Science and Technology

Collaborating Sponsors:

St. Olavs Hospital

Conditions:

Obesity

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Low-carb ketogenic diets have become extremely popular because of large weight loss in the short-term. Yet their potential benefits in preventing long-term weight regain have not been assessed in larg...

Eligibility Criteria

Inclusion

  • weight stable over the last three months (\<2 kg)
  • not currently dieting to lose weight
  • inactive lifestyle (less than 150 min of physical activity weekly.
  • Given that some of the variables of interest have been shown to be affected by the phase of menstrual cycle in normally ovulating women, namely appetite and resting metabolic rate, only women taking oral contraceptives, with regular menstrual cycles or post-menopausal will be included in the study

Exclusion

  • pregnancy
  • breast-feeding
  • drug or alcohol abuse within the last two years
  • clinically significant illness including diabetes, gastrointestinal (particularly cholelithiasis), kidney (GFR \<60) or liver disease, osteoporosis (T-score \<-2.5) and osteopenia (T-score \<-1.5)
  • treatment with antiosteoporotic drug
  • depression or other psychological disorders
  • eating disorders
  • milk intolerance
  • current medication known to affect appetite/metabolism or induce weight loss.
  • a planned surgery during the study period
  • participating in another research study

Key Trial Info

Start Date :

August 3 2020

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 10 2021

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT04382183

Start Date

August 3 2020

End Date

December 10 2021

Last Update

April 29 2022

Active Locations (1)

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Forsyningssenteret at NTNU

Trondheim, Norway