Status:

UNKNOWN

Better Delineation of CDK13 Related Phenotype and Epigenetic Signature.

Lead Sponsor:

University Hospital, Montpellier

Conditions:

Congenital Heart Defects

Dysmorphic Facial Features and Intellectual Developmental Disorder

Eligibility:

All Genders

Brief Summary

CDK13 related disorder is mainly characterised by developmental delay (DD) and intellectual disability (ID), ranging from mild to severe, and malformation syndrome. The aims of this study are first t...

Detailed Description

The investigators aim to better understand and delineate the genetic syndrome CDK13 This genetic disorder was described in Sepember 2016 in Nature Genetics (PMID 27479907). Since this first publicati...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • \- CDK13 intragenic pathogenic SNV (Single Nucleotide Variant)
  • Exclusion criteria:
  • no pathogenic SNV in CDK13
  • no consent for the study

Exclusion

    Key Trial Info

    Start Date :

    November 1 2019

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    December 30 2020

    Estimated Enrollment :

    100 Patients enrolled

    Trial Details

    Trial ID

    NCT04382573

    Start Date

    November 1 2019

    End Date

    December 30 2020

    Last Update

    May 14 2020

    Active Locations (1)

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    UH Montpellier

    Montpellier, France, 34295