Status:
COMPLETED
Relationship Between LRG and Periodontal Disease
Lead Sponsor:
Aydin Adnan Menderes University
Collaborating Sponsors:
Giresun University
Bulent Ecevit University
Conditions:
Periodontitis
Acute-Phase Response
Eligibility:
All Genders
26-49 years
Phase:
NA
Brief Summary
This study aimed to investigate gingival crevicular fluid (GCF) and serum levels of LRG, interleukin (IL)-6 and tumor necrosis factor (TNF)-α in patients with periodontitis before and after non-surgic...
Detailed Description
Twenty-five stage 3 periodontitis and twenty-five periodontally healthy individuals were enrolled in the study. Clinical periodontal measurements were recorded; periodontitis patients received non-sur...
Eligibility Criteria
Inclusion
- 25-50 years of age
- having at least 20 natural teeth, excluding third molars
- having no systemic disease
- non-smokers
- criteria for healthy control group: BOP \< 10% and PD ≤ 3 mm without clinical attachment loss or radiographic sign of alveolar bone destruction
- criteria for stage 3 periodontitis group: interdental CAL ≥ 5 mm at least 2 non-adjacent teeth, PD ≥ 6 mm and radiographic bone loss extending to the mid-third of the root or beyond.
Exclusion
- having any systemic diseases,
- smoking
- current pregnancy or lactation
- a history of periodontal treatment in the past 6 months
- using antibiotic, anti-inflammatory drugs or any other drugs within the past 6 months.
Key Trial Info
Start Date :
September 30 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 15 2020
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04383561
Start Date
September 30 2019
End Date
February 15 2020
Last Update
May 12 2020
Active Locations (1)
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1
Giresun University
Giresun, Turkey (Türkiye), 28100