Status:
COMPLETED
Effect of Intratracheal Dexmedetomidine Administration on Recovery From General Anesthesia in Pediatrics Undergoing Lower Abdominal Surgery:
Lead Sponsor:
Assiut University
Conditions:
Intratracheal
Dexmedetomidine
Eligibility:
All Genders
1-6 years
Phase:
PHASE2
PHASE3
Brief Summary
The incidence of intratracheal tube-induced laryngeal irritation, including coughing, bucking, and cardiovascular stimulation, on emergence from general anesthesia has been reported to occur in 38% an...
Detailed Description
Several strategies have been reported to facilitate smoother extubation, such as intravenous lidocaine, remifentanil, and dexmedetomidine. Dexmedetomidine is a potent, alpha-2-selective adrenoceptor a...
Eligibility Criteria
Inclusion
- ASA physical status classification I-II.
- Scheduled for lower abdominal surgeries e.g. congenital hernia repair and correction of penile hypospadias under general anesthesia (GA).
Exclusion
- Younger than 1 year and older than 6 years of age,
- ASA score of III to IV.
- Parental refusal
- Allergy or contraindication to studied medication or anesthetic agents
- Patients with respiratory disease, heart disorders which might represent risk factors of potential complications of Dexmedetomidine such as bradycardia, hepatic or renal insufficiency.
Key Trial Info
Start Date :
June 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2023
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04385602
Start Date
June 1 2020
End Date
January 1 2023
Last Update
June 13 2023
Active Locations (1)
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1
Assiut governorate
Asyut, Egypt