Status:
UNKNOWN
Biomarkers of Acute Kidney Injury Following Cardiac Surgery
Lead Sponsor:
University of Saskatchewan
Conditions:
Novel Biomarkers of Acute Kidney Injury Following Cardiac Surgery
Eligibility:
All Genders
18-85 years
Brief Summary
Acute kidney injury occurs in up to 30% of patients undergoing cardiac surgery. Cardiac surgery associated-acute kidney injury (CSA-AKI) is characterized by a sudden and sustained decrease in renal fu...
Detailed Description
Cardiopulmonary bypass (CPB), although essential to the performance of most cardiac operations, has been shown to cause injury to other organs, particularly to the kidneys and brain. Matrix Metallopro...
Eligibility Criteria
Inclusion
- The inclusion criteria consisted of both sexes, 18-85 years of age, undergoing elective or urgent cardiac surgery with a hemoglobin (Hgb) \>100 g/L.
Exclusion
- The exclusion criteria included were patients for emergent surgery, pre-existing chronic kidney disease (eGFR\<30 mL/min) on dialysis or prescribed nephrotoxic mediations.
Key Trial Info
Start Date :
January 6 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
February 1 2022
Estimated Enrollment :
400 Patients enrolled
Trial Details
Trial ID
NCT04387149
Start Date
January 6 2020
End Date
February 1 2022
Last Update
May 13 2020
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
University of Saskatchewan
Saskatoon, Saskatchewan, Canada, S7N 0W8