Status:
UNKNOWN
The Microbiota in Kidney Donation and Transplantation
Lead Sponsor:
Royal Free Hospital NHS Foundation Trust
Collaborating Sponsors:
University College, London
Conditions:
Kidney Diseases
Kidney Transplant Failure and Rejection
Eligibility:
All Genders
18+ years
Brief Summary
The human gastrointestinal tract harbours \~40 trillion microbial cells, far outnumbering the cell number, and therefore the genetic content of its host. How this genetically diverse bacterial (collec...
Eligibility Criteria
Inclusion
- All adult (≥18 years old) undergoing living donor nephrectomy or kidney transplantation. Patients willing to provide samples including Urine, Blood, Faecal samples.
- Participant able to give Informed Consent
- All patients will be at least 18 years old
- Patients will either be a live renal transplant donor or a renal transplant recipient on the waiting list to have or will have had an ABO-blood group compatible renal transplant.
- Patients attending hospital clinics at participating centre for routine clinical follow -up.
- Patients willing to comply with study procedures and willing to provide blood, faecal and urine samples.
Exclusion
- Patients under the age of 18 years
- Patients unable to give informed consent
- Patients not able to comply with study procedures or follow-up visits
- Patients that are not a live renal donor or that are not on the waiting list to have or have not had an ABO blood group compatible renal transplant and are not attending hospital outpatient clinics at participating study centres for routine clinical follow-up.
Key Trial Info
Start Date :
March 1 2020
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2025
Estimated Enrollment :
130 Patients enrolled
Trial Details
Trial ID
NCT04388930
Start Date
March 1 2020
End Date
June 1 2025
Last Update
December 14 2023
Active Locations (1)
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1
Royal Free London NHS Trust
London, United Kingdom, NW3 2QG