Status:
RECRUITING
OCT-Angiography and Adaptive Optics in Patients With Memory Impairment
Lead Sponsor:
Fondation Ophtalmologique Adolphe de Rothschild
Conditions:
Amnesia
Alzheimer Disease
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Studies suggest an association between retinal abnormalities and NCD (Neuro Cognitive Disorders) whether they are linked to proven or prodromal Alzheimer's disease (aMCI : amnestic mild cognitive impa...
Eligibility Criteria
Inclusion
- Patient presenting in memory consultation for memory complaint or person accompanying a patient in memory consultation for memory complaint
Exclusion
- pregnant or lactating women
- history of known non-degenerative neurological pathology (tumor, stroke territorial, in particular multiple sclerosis)
- history of retinal pathology
- ametropia greater in absolute value than 3 diopters on the sphere, or/and 1.5 diopters on the cylinder.
- history of taking ethambutol for more than 2 months
- history of takingsynthetic antimalarial for more than 2 years
- Mini Mental State Score (MMS) and / or Montreal Cognitive Assessment (MoCA) \<10 for patients and 26 for accompanying persons
- MRI contraindication (for patients only)
Key Trial Info
Start Date :
June 26 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
450 Patients enrolled
Trial Details
Trial ID
NCT04389437
Start Date
June 26 2020
End Date
June 1 2026
Last Update
September 29 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hôpital Fondation A. de Rothschild
Paris, France, 75019